منابع مشابه
THE RELATIONSHIP BETWEEN ALUMINIUM TOXICITY AND IRON METABOLISM IN RATS
The relationship between aluminium toxicity and iron metabolism was studied. Male rats were exposed to aluminium by daily intraperitoneal injection of 40pmolelkg body weight. After 45 days, aluminium intoxified rats had a significant loweredserum ferritin (55%), iron (42%), TIBC (25%) and hemoglobin(31%). At thesame time the serum ceruloplasmin level was elevated by 60%. This result shows t...
متن کاملIron metabolism; utilization of intravenous radioactive iron.
T HE HUMAN body shows great economy in its handling of iron. Only small amounts of iron arefound in the excreta, and these amounts cannot be appreciably increased through loading body iron stores by oral ingestion,’ by parenteral iron administration2 or by multiple blood transfusions.3 These observations imply that iron is rigidly conserved by the body and that no attention need be directed tow...
متن کاملIRON METABOLISM Iron overload and chelation
Iron is one of the most common elements in nature. As a transition metal it is very efficient in electron transport and redox reactions. The proteins and enzymes in which iron is an essential component play a key role in respiration, energy production, detoxification of harmful oxygen species and cell replication. Despite the abundance of iron in nature, the solubility of its stable ferric form...
متن کاملIron Metabolism Utilization of Intravenous Radioactive Iron
T HE HUMAN body shows great economy in its handling of iron. Only small amounts of iron arefound in the excreta, and these amounts cannot be appreciably increased through loading body iron stores by oral ingestion,’ by parenteral iron administration2 or by multiple blood transfusions.3 These observations imply that iron is rigidly conserved by the body and that no attention need be directed tow...
متن کاملHemochromatosis and Iron Metabolism
Hereditary hemochromatosis Hereditary hemochromatosis (HH) is characterized by abnormal iron absorption from the diet resulting in progressive iron overload, causing tissue damage of several organs, particularly the liver (1). Historically HH has been regarded as an extremely rare inborn error of metabolism causing "bronze diabetes", liver cirrhosis and hepatocellular carcinoma due to heavy iro...
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ژورنال
عنوان ژورنال: Blood
سال: 1950
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v5.11.983.983